INTS12 antibody (N-Term)

Catalog No. ABIN2784469

Product Details anti-INTS12 Antibody

Target: INTS12 (Integrator Complex Subunit 12 (INTS12))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INTS12 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DESLARGIDS SYRPSQKDVE PPKISSTKNI SIKQEPKISS SLPSGNNNGK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against INTS12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human INTS12

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 462 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for INTS12

Target: INTS12 (Integrator Complex Subunit 12 (INTS12))

Alternative Name: INTS12 (INTS12 Products)

Synonyms: INT12 antibody, PHF22 antibody, GB14117 antibody, fi17f05 antibody, wu:fi17f05 antibody, zgc:86602 antibody, NV50096 antibody, 1110020M19Rik antibody, 2810027J24Rik antibody, 4930529N21Rik antibody, A230056J18Rik antibody, AI666778 antibody, Phf22 antibody, integrator complex subunit 12 antibody, integrator complex subunit 12 S homeolog antibody, INTS12 antibody, LOC409806 antibody, ints12 antibody, ints12.S antibody, CpipJ_CPIJ008030 antibody, Ints12 antibody, Tsp_11238 antibody, Tsp_11342 antibody, Tsp_11345 antibody

Background: INTS12 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1) and U2 (RNU2).INTS12 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A, MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1, MIM 180680) and U2 (RNU2, MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM].
Alias Symbols: INT12, PHF22, SBBI22
Protein Interaction Partner: POLR2C, APP, SUMO2, UBC, INTS10, INTS5, INTS3, INTS6, INTS1,
Protein Size: 462

Molecular Weight: 49 kDa

Gene ID: 57117

NCBI Accession: NM_020395, NP_065128

UniProt: Q96CB8