INTS12 antibody (C-Term)

Catalog No. ABIN2784468

Product Details anti-INTS12 Antibody

Target: INTS12 (Integrator Complex Subunit 12 (INTS12))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INTS12 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SGNGNSATAG PTGSITSKTT SETSSSTSAS LKGPTSQESQ LNAMKRLQMV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 91%

Characteristics: This is a rabbit polyclonal antibody against Ints12. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Rat Ints12

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for INTS12

Target: INTS12 (Integrator Complex Subunit 12 (INTS12))

Alternative Name: Ints12 (INTS12 Products)

Synonyms: INT12 antibody, PHF22 antibody, GB14117 antibody, fi17f05 antibody, wu:fi17f05 antibody, zgc:86602 antibody, NV50096 antibody, 1110020M19Rik antibody, 2810027J24Rik antibody, 4930529N21Rik antibody, A230056J18Rik antibody, AI666778 antibody, Phf22 antibody, integrator complex subunit 12 antibody, integrator complex subunit 12 S homeolog antibody, INTS12 antibody, LOC409806 antibody, ints12 antibody, ints12.S antibody, CpipJ_CPIJ008030 antibody, Ints12 antibody, Tsp_11238 antibody, Tsp_11342 antibody, Tsp_11345 antibody

Background: Ints12 is a component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.
Alias Symbols: Phf22
Protein Size: 461

Molecular Weight: 50 kDa

Gene ID: 295448

NCBI Accession: NM_001007640, NP_001007641

UniProt: Q68FR3