MAS1 antibody (Middle Region)

Catalog No. ABIN2784455

Product Details anti-MAS1 Antibody

Target: MAS1 (MAS1 Oncogene (MAS1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: RPKYQSALVC ALLWALSCLV TTMEYVMCID REEESHSRND CRAVIIFIAI

Predicted Reactivity: Guinea Pig: 77%, Human: 100%, Mouse: 77%, Rat: 77%

Characteristics: This is a rabbit polyclonal antibody against MAS1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MAS1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 325 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAS1

Target: MAS1 (MAS1 Oncogene (MAS1))

Alternative Name: MAS1 (MAS1 Products)

Synonyms: MAS antibody, Mas-1 antibody, c-mas antibody, MAS1 antibody, MAS1 proto-oncogene, G protein-coupled receptor antibody, MAS1 oncogene antibody, proto-oncogene Mas antibody, MAS1 antibody, Mas1 antibody, LOC703105 antibody

Background: The structure of MAS1 indicates that it belongs to the class of receptors that are coupled to GTP-binding proteins and share a conserved structural motif, which is described as a '7-transmembrane segment' following the prediction that these hydrophobic segments form membrane-spanning alpha-helices. The MAS1 protein may be a receptor that, when activated, modulates a critical component in a growth-regulating pathway to bring about oncogenic effects.The structure of the MAS1 product indicates that it belongs to the class of receptors that are coupled to GTP-binding proteins and share a conserved structural motif, which is described as a '7-transmembrane segment' following the prediction that these hydrophobic segments form membrane-spanning alpha-helices. The MAS1 protein may be a receptor that, when activated, modulates a critical component in a growth-regulating pathway to bring about oncogenic effects.
Alias Symbols: MAS, MGC119966
Protein Interaction Partner: SNTA1, AGT,
Protein Size: 325

Molecular Weight: 37 kDa

Gene ID: 4142

NCBI Accession: NM_002377, NP_002368

UniProt: P04201

Pathways: ACE Inhibitor Pathway, Regulation of Carbohydrate Metabolic Process