PTP4A3 antibody (Middle Region)
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- Target See all PTP4A3 Antibodies
- PTP4A3 (Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PTP4A3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LGRAPVLVAL ALIESGMKYE DAIQFIRQKR RGAINSKQLT YLEKYRPKQR
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against PTP4A3. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PTP4A3
- Top Product
- Discover our top product PTP4A3 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 173 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PTP4A3 (Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))
- Alternative Name
- PTP4A3 (PTP4A3 Products)
- Synonyms
- PRL-3 antibody, PRL-R antibody, PRL3 antibody, wu:fc54b05 antibody, wu:fv52d11 antibody, zgc:77109 antibody, prl-3 antibody, prl3 antibody, ptpcaax3 antibody, PTP4A3 antibody, AV088979 antibody, Prl-3 antibody, pPtp4a3 antibody, protein tyrosine phosphatase type IVA, member 3 antibody, protein tyrosine phosphatase type IVA, member 3 L homeolog antibody, protein tyrosine phosphatase 4a3 antibody, PTP4A3 antibody, ptp4a3 antibody, ptp4a3.L antibody, Ptp4a3 antibody
- Background
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PTP4A3 belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contains a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth.The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist.
Alias Symbols: PRL-3, PRL-R, PRL3
Protein Interaction Partner: ELAVL1, FNTB, FNTA, IPO4, MMS19, NCAPG, SMAP1, SRPRB, XPO5, TTC27, FANCI, ATAD3A, TMEM33, HEATR1, DNAAF5, TNPO2, CNNM3, KIAA1279, RAB3GAP2, NUP188, KIAA0368, XPO7, GCN1L1, SMC2, LRPPRC, UBE4A, AIFM1, USO1, ABCD3, PSMD3, PRPSAP1, POLD1, HNRNPM, MSH2, MCM3,
Protein Size: 173 - Molecular Weight
- 19 kDa
- Gene ID
- 11156
- NCBI Accession
- NM_032611, NP_116000
- UniProt
- O75365
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