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NAGS antibody (C-Term)

NAGS Reactivity: Human, Mouse, Rat, Dog, Pig, Rabbit, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2784450
  • Target See all NAGS Antibodies
    NAGS (N-Acetylglutamate Synthase (NAGS))
    Binding Specificity
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 9
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog, Pig, Rabbit, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio)
    Host
    • 8
    • 1
    Rabbit
    Clonality
    • 9
    Polyclonal
    Conjugate
    • 9
    This NAGS antibody is un-conjugated
    Application
    • 9
    • 4
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    YLDKFVVSSS RQGQGSGQML WECLRRDLQT LFWRSRVTNP INPWYFKHSD
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
    Characteristics
    This is a rabbit polyclonal antibody against NAGS. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human NAGS
    Top Product
    Discover our top product NAGS Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 534 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    NAGS (N-Acetylglutamate Synthase (NAGS))
    Alternative Name
    NAGS (NAGS Products)
    Synonyms
    VF0585 antibody, AGAS antibody, ARGA antibody, 1700120E20Rik antibody, argA antibody, RGD1565783 antibody, N-acetylglutamate synthase antibody, amino-acid acetyltransferase ArgA antibody, argA antibody, ECs3675 antibody, VP2371 antibody, Psyr_0254 antibody, Sde_0360 antibody, NAGS antibody, Nags antibody
    Background
    NAGS is a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.
    Alias Symbols: AGAS, ARGA, MGC133025
    Protein Interaction Partner: TMEM39B,
    Protein Size: 534
    Molecular Weight
    58 kDa
    Gene ID
    162417
    NCBI Accession
    NM_153006, NP_694551
    UniProt
    Q8N159
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