NAGS antibody (C-Term)
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- Target See all NAGS Antibodies
- NAGS (N-Acetylglutamate Synthase (NAGS))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Dog, Pig, Rabbit, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NAGS antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- YLDKFVVSSS RQGQGSGQML WECLRRDLQT LFWRSRVTNP INPWYFKHSD
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- Characteristics
- This is a rabbit polyclonal antibody against NAGS. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human NAGS
- Top Product
- Discover our top product NAGS Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 534 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- NAGS (N-Acetylglutamate Synthase (NAGS))
- Alternative Name
- NAGS (NAGS Products)
- Synonyms
- VF0585 antibody, AGAS antibody, ARGA antibody, 1700120E20Rik antibody, argA antibody, RGD1565783 antibody, N-acetylglutamate synthase antibody, amino-acid acetyltransferase ArgA antibody, argA antibody, ECs3675 antibody, VP2371 antibody, Psyr_0254 antibody, Sde_0360 antibody, NAGS antibody, Nags antibody
- Background
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NAGS is a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.
Alias Symbols: AGAS, ARGA, MGC133025
Protein Interaction Partner: TMEM39B,
Protein Size: 534 - Molecular Weight
- 58 kDa
- Gene ID
- 162417
- NCBI Accession
- NM_153006, NP_694551
- UniProt
- Q8N159
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