WDFY3 antibody (C-Term)

Catalog No. ABIN2784358

Product Details anti-WDFY3 Antibody

Target: WDFY3 (WD Repeat and FYVE Domain Containing 3 (WDFY3))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse, Cow, Dog, Pig, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDFY3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EKLADAVRFL GCFSDLRKIS AMNVFPSNTQ PFQRLLEEDV ISIESVSPTL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against WDFY3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human WDFY3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 795 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-WDFY3 antibody (ABIN2784358)

Yao, Jia, Feathers, Lin, Khan, Klionsky, Ferguson, Zacks: "Autophagy-mediated catabolism of visual transduction proteins prevents retinal degeneration." in: Autophagy, Vol. 12, Issue 12, pp. 2439-2450, (2016) (PubMed).

Target Details for WDFY3

Target: WDFY3 (WD Repeat and FYVE Domain Containing 3 (WDFY3))

Alternative Name: WDFY3 (WDFY3 Products)

Synonyms: ALFY antibody, ZFYVE25 antibody, 2610509D04Rik antibody, AW319683 antibody, B930017C24 antibody, BWF1 antibody, Bchs antibody, D5Ertd66e antibody, Ggtb3 antibody, mKIAA0993 antibody, WDFY family member 4 antibody, WD repeat and FYVE domain containing 3 antibody, WD repeat and FYVE domain-containing protein 3 antibody, WDFY4 antibody, WDFY3 antibody, MGYG_03998 antibody, Wdfy3 antibody

Background: WDFY3 is a protein which contains WD repeats and an FYVE domain. WDFY3 might target cytosolic protein aggregates for autophagic degradation.This gene encodes a protein which contains WD repeats and an FYVE domain. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
Alias Symbols: ALFY, KIAA0993, MGC16461, ZFYVE25
Protein Interaction Partner: CEP76, TRIM39, ZBTB44, PRMT6, SUV39H1, PRMT1, SQSTM1, TRAF6, BAG3, EEF2K, ATG16L1, ATG5, ATG12, MAP1LC3A, UBC,
Protein Size: 795

Molecular Weight: 90 kDa

Gene ID: 23001

NCBI Accession: NM_178583, NP_848698

UniProt: Q8IZQ1