TCEAL7 antibody (Middle Region)

Catalog No. ABIN2784332

Product Details anti-TCEAL7 Antibody

Target: TCEAL7 (Transcription Elongation Factor A (SII)-Like 7 (TCEAL7))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Cow, Dog, Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCEAL7 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RLLQSLEEFK EDIDYRHFKG EEMTGEEEEM ERCLEEIRSL RKKFRALHSN

Predicted Reactivity: Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 100%, Rat: 93%, Yeast: 83%

Characteristics: This is a rabbit polyclonal antibody against Tceal7. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 98 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TCEAL7

Target: TCEAL7 (Transcription Elongation Factor A (SII)-Like 7 (TCEAL7))

Alternative Name: Tceal7 (TCEAL7 Products)

Synonyms: MPMGp800C04260Q003 antibody, 1110018P05Rik antibody, transcription elongation factor A like 7 antibody, transcription elongation factor A (SII)-like 7 antibody, TCEAL7 antibody, Tceal7 antibody

Background: Tceal7 plays a role in the negative regulation of NF-kappa-B signaling at the basal level by modulating transcriptional activity of NF-kappa-B on its target gene promoters. Tceal7 associates with cyclin D1 promoter containing Myc E-box sequence and transcriptionally represses cyclin D1 expression. Tceal7 regulates telomerase reverse transcriptase expression and telomerase activity in both ALT (alternative lengthening of telomeres)and telomerase-positive cell lines.
Alias Symbols: 1110018P05Rik, AI118095
Protein Size: 98

Molecular Weight: 10 kDa

Gene ID: 100040972

NCBI Accession: NM_001127169, NP_001120641

UniProt: A3KGA4