ARID5B antibody (C-Term)

Catalog No. ABIN2784295

Product Details anti-ARID5B Antibody

Target: ARID5B (AT Rich Interactive Domain 5B (MRF1-Like) (ARID5B))

Binding Specificity: C-Term

Reactivity: Human, Rabbit, Rat, Cow, Horse, Guinea Pig, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARID5B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VSPLDPSKEV SGKEKASEQE SEGSKAAHGG HSGGGSEGHK LPLSSPIFPG

Predicted Reactivity: Cow: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ARID5B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ARID5B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1188 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ARID5B

Target: ARID5B (AT Rich Interactive Domain 5B (MRF1-Like) (ARID5B))

Alternative Name: ARID5B (ARID5B Products)

Synonyms: ARID5B antibody, DKFZp469H121 antibody, DKFZP469L1210 antibody, DESRT antibody, MRF-2 antibody, MRF2 antibody, 4930580B11 antibody, 5430435G07Rik antibody, AI467247 antibody, Desrt antibody, Mrf2 antibody, Mrf2alpha antibody, Mrf2beta antibody, AT-rich interaction domain 5B antibody, AT-rich interaction domain 5B S homeolog antibody, AT rich interactive domain 5B (MRF1-like) antibody, ARID5B antibody, arid5b.S antibody, Arid5b antibody

Background: ARID5B is a DNA-binding protein that binds to the 5'-AATA[CT]-3' core sequence. ARID5B probably acts as a transcription regulator. ARID5B represses the cytomegalovirus enhancer. Overexpression of ARID5B leads to induction of smooth muscle marker genes, suggesting that it may act as a regulator of smooth muscle cell differentiation and proliferation. ARID5B may be involved in lipid stores.
Alias Symbols: DESRT, FLJ21150, MRF2, MRF-2
Protein Interaction Partner: UBC, SOX2, HDAC2, HDAC1, SUMO1, CAND1, ISG15, ELAVL1, SUMO2,
Protein Size: 1188

Molecular Weight: 132 kDa

Gene ID: 84159

NCBI Accession: NM_032199, NP_115575

UniProt: Q14865

Pathways: Platelet-derived growth Factor Receptor Signaling