SPRY4 antibody (Middle Region)
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- Target See all SPRY4 Antibodies
- SPRY4 (Sprouty RTK Signaling Antagonist 4 (SPRY4))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SPRY4 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LCYLPATGCV KLAQRGYDRL RRPGCRCKHT NSVICKAASG DAKTSRPDKP
- Predicted Reactivity
- Cow: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 79%
- Characteristics
- This is a rabbit polyclonal antibody against SPRY4. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human SPRY4
- Top Product
- Discover our top product SPRY4 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 322 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SPRY4 (Sprouty RTK Signaling Antagonist 4 (SPRY4))
- Alternative Name
- SPRY4 (SPRY4 Products)
- Synonyms
- SPRY4 antibody, LOC100218545 antibody, HH17 antibody, A030006O18Rik antibody, sprouty4 antibody, sprouty RTK signaling antagonist 4 antibody, sprouty (Drosophila) homolog 4 antibody, sprouty homolog 4 (Drosophila) antibody, Spry4 antibody, SPRY4 antibody, spry4 antibody
- Background
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SPRY4 is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. It is positioned upstream of RAS (see HRAS, MIM 190020) activation and impairs the formation of active GTP-RAS (Leeksma et al., 2002 [PubMed 12027893]).
Alias Symbols: -
Protein Interaction Partner: GRB2, SPRY2, SPRY4, TESK1, RAF1, CBL,
Protein Size: 322 - Molecular Weight
- 35 kDa
- Gene ID
- 81848
- NCBI Accession
- NM_030964, NP_112226
- UniProt
- Q9C004
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