PTOV1 antibody (N-Term)

Catalog No. ABIN2784251

Product Details anti-PTOV1 Antibody

Target: PTOV1 (Prostate Tumor Overexpressed 1 (PTOV1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTOV1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: DSTAKLKRTL PCQAYVNQGE NLETDQWPQK LIMQLIPQQL LTTLGPLFRN

Predicted Reactivity: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PTOV1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PTOV1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 416 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PTOV1 antibody (ABIN2784251)

Youn, Park, Kim, Um: "PTOV1 antagonizes MED25 in RAR transcriptional activation." in: Biochemical and biophysical research communications, Vol. 404, Issue 1, pp. 239-44, (2011) (PubMed).

Target Details for PTOV1

Target: PTOV1 (Prostate Tumor Overexpressed 1 (PTOV1))

Alternative Name: PTOV1 (PTOV1 Products)

Synonyms: 1110030G05Rik antibody, AU041779 antibody, Gcap3 antibody, ACID2 antibody, PTOV-1 antibody, prostate tumor over expressed gene 1 antibody, prostate tumor overexpressed 1 antibody, Ptov1 antibody, PTOV1 antibody

Background: PTOV1 belongs to the Mediator complex subunit 25 family, PTOV1 subfamily. It may activate transcription and is required for nuclear translocation of FLOT1. PTOV1 promotes cell proliferation.
Alias Symbols: DKFZP586I111, MGC71475, ACID2, PTOV-1
Protein Interaction Partner: UBC, GNB2L1, FLOT1, RPS6, CUL2, USP16, HDAC6, CREBBP, BECN1, TMCC2, PIN1, SPTAN1, DMTN, SFN,
Protein Size: 416

Molecular Weight: 47 kDa

Gene ID: 53635

NCBI Accession: NM_017432, NP_059128

UniProt: Q86YD1