COG5 antibody (N-Term)

Catalog No. ABIN2784225

Product Details anti-COG5 Antibody

Target: COG5 (Component of Oligomeric Golgi Complex 5 (COG5))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COG5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MGWVGGRRRD SASPPGRSRS AADDINPAPA NMEGGGGSVA VAGLGARGSG

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against COG5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human COG5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 860 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for COG5

Target: COG5 (Component of Oligomeric Golgi Complex 5 (COG5))

Alternative Name: COG5 (COG5 Products)

Synonyms: CDG2I antibody, GOLTC1 antibody, GTC90 antibody, 5430405C01Rik antibody, C87247 antibody, D18362 antibody, component of oligomeric golgi complex 5 antibody, COG5 antibody, Cog5 antibody

Background: COG5 is required for normal Golgi function.Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi (COG) complex, which includes COG5 (Ungar et al., 2002 [PubMed 11980916]).[supplied by OMIM].
Alias Symbols: GOLTC1, GTC90, CDG2I
Protein Interaction Partner: UBC, COG7, EGFR, VCP, COG8, COG3, COG6, COG4, COG2, COG1, TRAF5, Poc1b, Nek9, RAC1, APC, MEFV,
Protein Size: 860

Molecular Weight: 95 kDa

Gene ID: 10466

NCBI Accession: NM_006348, NP_006339