ING2 antibody (N-Term)

Catalog No. ABIN2784201

Product Details anti-ING2 Antibody

Target: ING2 (Inhibitor of Growth Family, Member 2 (ING2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Horse, Cow, Dog, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ING2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TCYVQDYLEC VESLPHDMQR NVSVLRELDN KYQETLKEID DVYEKYKKED

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against ING2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ING2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 280 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ING2

Target: ING2 (Inhibitor of Growth Family, Member 2 (ING2))

Alternative Name: ING2 (ING2 Products)

Background: This gene is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis.
Alias Symbols: ING1L, p33ING2
Protein Interaction Partner: SIRT1, WDR5, PRMT5, HIST3H3, UBC, HDAC1, APP, SMURF1, SUMO1, COPS2, TP53, SKIL, SMAD2, EP300, PCNA, HIST2H4A, SMURF2, SMAD1, HHT2, SAP30, HHT1, SIN3A, BRMS1L, SAP130, SUDS3, ARID4B, SMARCC2, SMARCC1, SMARCB1, RBBP7, RBBP4, ARID4A, HDAC2, ACTL6A,
Protein Size: 280

Molecular Weight: 33 kDa

Gene ID: 3622

NCBI Accession: NM_001564, NP_001555

UniProt: Q9H160

Pathways: Chromatin Binding, Autophagy, Negative Regulation of intrinsic apoptotic Signaling