COLEC12 antibody (Middle Region)

Catalog No. ABIN2784130

Product Details anti-COLEC12 Antibody

Target: COLEC12 (Collectin Sub-Family Member 12 (COLEC12))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Rabbit, Guinea Pig, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COLEC12 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AGERGPIGPA GPPGERGGKG SKGSQGPKGS RGSPGKPGPQ GPSGDPGPPG

Predicted Reactivity: Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against COLEC12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human COLEC12

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 742 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for COLEC12

Target: COLEC12 (Collectin Sub-Family Member 12 (COLEC12))

Alternative Name: COLEC12 (COLEC12 Products)

Synonyms: COLEC12 antibody, CLP1 antibody, NSR2 antibody, SCARA4 antibody, SRCL antibody, CL-P1 antibody, Scara4 antibody, hm:zeh0853 antibody, id:ibd2826 antibody, sb:cb377 antibody, si:ch211-212m21.5 antibody, collectin subfamily member 12 antibody, collectin sub-family member 12 antibody, COLEC12 antibody, colec12 antibody, Colec12 antibody

Background: COLEC12 is a member of the C-lectin family,!!proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that can bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. In addition, these receptors can recognize oxidized phospholipids so they may also participate in removing oxidatively damaged or apoptotic cells.This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that can bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. In addition, these receptors can recognize oxidized phospholipids so they may also participate in removing oxidatively damaged or apoptotic cells.
Alias Symbols: CLP1, NSR2, SCARA4, SRCL
Protein Interaction Partner: APP, EXOC1,
Protein Size: 742

Molecular Weight: 81 kDa

Gene ID: 81035

NCBI Accession: NM_130386, NP_569057

UniProt: Q5KU26

Pathways: Activation of Innate immune Response