MT-ND6 antibody (Middle Region)

Catalog No. ABIN2784118

Product Details anti-MT-ND6 Antibody

Target: MT-ND6 (Mitochondrially Encoded NADH Dehydrogenase 6 (MT-ND6))

Binding Specificity: Middle Region

Reactivity: Human, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MT-ND6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DGVVVVVNFN SVGSWMIYEG EGSGLIREDP IGAGALYDYG RWLVVVTGWT

Predicted Reactivity: Human: 100%, Pig: 93%

Characteristics: This is a rabbit polyclonal antibody against ND6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ND6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 174 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-MT-ND6 antibody (ABIN2784118)

Schüler-Toprak, Moehle, Skrzypczak, Ortmann, Treeck: "Effect of estrogen receptor β agonists on proliferation and gene expression of ovarian cancer cells." in: BMC cancer, Vol. 17, Issue 1, pp. 319, (2018) (PubMed).

Karamanlidis, Nascimben, Couper, Shekar, del Monte, Tian: "Defective DNA replication impairs mitochondrial biogenesis in human failing hearts." in: Circulation research, Vol. 106, Issue 9, pp. 1541-8, (2010) (PubMed).

Target Details for MT-ND6

Target: MT-ND6 (Mitochondrially Encoded NADH Dehydrogenase 6 (MT-ND6))

Alternative Name: ND6 (MT-ND6 Products)

Synonyms: MTND6 antibody, NADH6 antibody, mitochondrial NADH-ubiquinone oxidoreductase chain 6 antibody, NADH dehydrogenase, subunit 6 (complex I) antibody, NADH dehydrogenase subunit 6 antibody, NADH dehydrogenasesubunit 6 antibody, mt:ND6 antibody, ND6 antibody, nad6 antibody

Background: The exact function of ND6 remains unknown.
Alias Symbols: MTND6
Protein Interaction Partner: YME1L1, NDUFS3,
Protein Size: 174

Molecular Weight: 19 kDa

Gene ID: 4541

NCBI Accession: NP_536854

UniProt: P03923