MMEL1 antibody (Middle Region)

Catalog No. ABIN2784086

Product Details anti-MMEL1 Antibody

Target: MMEL1 (Membrane Metallo-Endopeptidase-Like 1 (MMEL1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMEL1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EVVVYGIPYL QNLENIIDTY SARTIQNYLV WRLVLDRIGS LSQRFKDTRV

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MMEL1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MMEL1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 770 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MMEL1

Target: MMEL1 (Membrane Metallo-Endopeptidase-Like 1 (MMEL1))

Alternative Name: MMEL1 (MMEL1 Products)

Synonyms: MMEL2 antibody, NEP2 antibody, NEPII antibody, NL1 antibody, NL2 antibody, SEP antibody, Mell1 antibody, Nl1 antibody, MMEL1 antibody, membrane metalloendopeptidase like 1 antibody, membrane metallo-endopeptidase-like 1 antibody, MMEL1 antibody, Mmel1 antibody, mmel1 antibody

Background: MMEL1 is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and homeostasis. MMEL1 is a type II transmembrane protein and is thought to be expressed as a secreted protein. The protein encoded by this gene is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and homeostasis. This protein is a type II transmembrane protein and is thought to be expressed as a secreted protein. This gene is expressed mainly in testis with weak expression in the brain, kidney, and heart.
Alias Symbols: MGC119454, MGC119455, MGC119456, MMEL2, NEPII, NL1, NL2, SEP, NEP2
Protein Size: 770

Molecular Weight: 88 kDa

Gene ID: 79258

NCBI Accession: NM_033467, NP_258428

UniProt: Q495T6