Surfeit 4 antibody (N-Term)

Catalog No. ABIN2784078

Product Details anti-Surfeit 4 Antibody

Target: Surfeit 4 (SURF4)

Binding Specificity: N-Term

Reactivity: Mouse, Human, Rat, Cow, Dog, Guinea Pig, Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Surfeit 4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GQNDLMGTAE DFADQFLRVT KQYLPHVARL CLISTFLEDG IRMWFQWSEQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against SURF4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SURF4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 269 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-Surfeit 4 antibody (ABIN2784078)

Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).

Target Details for Surfeit 4

Target: Surfeit 4 (SURF4)

Alternative Name: SURF4 (SURF4 Products)

Synonyms: CG6202 antibody, Dmel\\CG6202 antibody, SURF-4 antibody, Surf-4 antibody, SURF4 antibody, MGC88894 antibody, GB14656 antibody, Surf4 antibody, DKFZp459A164 antibody, ERV29 antibody, erv29 antibody, surf4 antibody, zgc:65806 antibody, zgc:77007 antibody, AL033340 antibody, AL033373 antibody, Surfeit 4 antibody, surfeit 4 antibody, surfeit 4, gene 1 antibody, surfeit locus protein 4 homolog antibody, surfeit 4, gene 1 L homeolog antibody, surfeit gene 4 antibody, Surf4 antibody, SURF4 antibody, surf4.1 antibody, LOC552234 antibody, surf4.1.L antibody, surf4 antibody

Background: SURF4 is a conserved integral membrane protein containing multiple putative transmembrane regions. In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). The specific function of this protein has not been determined but its yeast homolog is directly required for packaging glycosylated pro-alpha-factor into COPII vesicles. This gene is located in the surfeit gene cluster, which is comprised of very tightly linked housekeeping genes that do not share sequence similarity. The encoded protein is a conserved integral membrane protein containing multiple putative transmembrane regions. In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). The specific function of this protein has not been determined but its yeast homolog is directly required for packaging glycosylated pro-alpha-factor into COPII vesicles. This gene uses multiple polyadenylation sites, resulting in transcript length variation. The existence of alternatively spliced transcript variants has been suggested, but their validity has not been determined.
Alias Symbols: ERV29, FLJ22993, MGC102753
Protein Interaction Partner: UBC, LGR4, MMS19, env, UBL4A, VKORC1, SRSF5, SRSF1, SAFB, S100A9, PSAP, P4HB, NPM1, NHP2L1, NFIA, SEPT2, HSPA5, SEPT7, NDUFB11, HP1BP3, PHGDH, SF3B1, NCSTN, SAP18, SRSF7, TMEM173, UNC93B1, C20orf24, SERINC3, DEGS1,
Protein Size: 269

Molecular Weight: 30 kDa

Gene ID: 6836

NCBI Accession: NM_033161, NP_149351

UniProt: O15260