Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

DISP1 antibody (Middle Region)

DISP1 Reactivity: Human, Mouse, Rat, Horse, Rabbit, Zebrafish (Danio rerio), Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2784069
  • Target See all DISP1 Antibodies
    DISP1 (Dispatched Homolog 1 (DISP1))
    Binding Specificity
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    Human, Mouse, Rat, Horse, Rabbit, Zebrafish (Danio rerio), Pig
    Host
    • 5
    • 1
    Rabbit
    Clonality
    • 6
    Polyclonal
    Conjugate
    • 6
    This DISP1 antibody is un-conjugated
    Application
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    FVLCDVWNYT KFDKPHAETS ETVSITLQHA ALSMFVTSFT TAAAFYANYV
    Predicted Reactivity
    Horse: 93%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 100%, Rat: 86%, Zebrafish: 79%
    Characteristics
    This is a rabbit polyclonal antibody against DISP1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human DISP1
    Top Product
    Discover our top product DISP1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 1524 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    DISP1 (Dispatched Homolog 1 (DISP1))
    Alternative Name
    DISP1 (DISP1 Products)
    Synonyms
    DISP1 antibody, DISPA antibody, 1190008H24Rik antibody, DispA antibody, con antibody, zgc:111866 antibody, dispatched antibody, dispatched RND transporter family member 1 antibody, dispatched homolog 1 (Drosophila) antibody, CpipJ_CPIJ008642 antibody, DISP1 antibody, Disp1 antibody, disp1 antibody
    Background
    DISP1 functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal.The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo.
    Alias Symbols: DISPA, DKFZP434I0428, FLJ43740, MGC104180, MGC13130, MGC16796
    Protein Interaction Partner: LAPTM5, UBC,
    Protein Size: 1524
    Molecular Weight
    171 kDa
    Gene ID
    84976
    NCBI Accession
    NM_032890, NP_116279
    UniProt
    Q96F81
    Pathways
    Hedgehog Signaling
You are here:
Support