DIRC2 antibody (Middle Region)

Catalog No. ABIN2784064

Product Details anti-DIRC2 Antibody

Target: DIRC2 (Disrupted in Renal Carcinoma 2 (DIRC2))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DIRC2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AAESSRAHIK DRIEAVLYAE FGVVCLIFSA TLAYFPPRPP LPPSVAAASQ

Predicted Reactivity: Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against DIRC2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DIRC2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 478 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DIRC2

Target: DIRC2 (Disrupted in Renal Carcinoma 2 (DIRC2))

Alternative Name: DIRC2 (DIRC2 Products)

Synonyms: MGC80843 antibody, zgc:92095 antibody, rcc4 antibody, MGC69320 antibody, RCC4 antibody, disrupted in renal carcinoma 2 antibody, disrupted in renal carcinoma 2 L homeolog antibody, disrupted in renal carcinoma 2 (human) antibody, DIRC2 antibody, dirc2.L antibody, dirc2 antibody, Dirc2 antibody

Background: DIRC2 is a membrane-bound protein from the major facilitator superfamily of transporters. Disruption of DIRC2 by translocation has been associated with haplo-insufficiency and renal cell carcinomas. Alternatively spliced transcript variants have been described, but their biological validity has not yet been determined.This gene encodes a membrane-bound protein from the major facilitator superfamily of transporters. Disruption of this gene by translocation has been associated with haplo-insufficiency and renal cell carcinomas. Alternatively spliced transcript variants have been described, but their biological validity has not yet been determined. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence and transcripts to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.
Alias Symbols: FLJ14784, RCC4
Protein Size: 478

Molecular Weight: 52 kDa

Gene ID: 84925

NCBI Accession: NM_032839, NP_116228

UniProt: Q96SL1