ORAI2 antibody (Middle Region)

Catalog No. ABIN2784063

Product Details anti-ORAI2 Antibody

Target: ORAI2 (ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2))

Binding Specificity: Middle Region

Reactivity: Human, Cow, Rabbit, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ORAI2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IELAWGFSTV LGILLFLAEV VLLCWIKFLP VDARRQPGPP PGPGSHTGWQ

Predicted Reactivity: Cow: 86%, Dog: 93%, Human: 100%, Rabbit: 79%

Characteristics: This is a rabbit polyclonal antibody against ORAI2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ORAI2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 254 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ORAI2

Target: ORAI2 (ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2))

Alternative Name: ORAI2 (ORAI2 Products)

Background: ORAI2 is a multi-pass membrane protein, and it belongs to the Orai family. It is a Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)-selective current by synergy with the Ca(2+) sensor, STIM1.
Alias Symbols: C7orf19, CBCIP2, FLJ12474, FLJ14733, TMEM142B, MEM142B
Protein Interaction Partner: COPS6, MED31, SETDB1, UNC119, GDF9,
Protein Size: 254

Molecular Weight: 28 kDa

Gene ID: 80228

NCBI Accession: NM_032831, NP_116220

UniProt: Q96SN7