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FCRLA antibody (C-Term)

FCRLA Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN406100
  • Target See all FCRLA Antibodies
    FCRLA (Fc Receptor-Like A (FCRLA))
    Binding Specificity
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 11
    • 2
    Human
    Host
    • 7
    • 4
    • 2
    Rabbit
    Clonality
    • 13
    Polyclonal
    Conjugate
    • 13
    This FCRLA antibody is un-conjugated
    Application
    • 13
    • 3
    • 1
    Western Blotting (WB)
    Sequence
    MPDPHLYHQM GLLLKHMQDV RVLLGHLLME LRELSGHRKP GTTKATAE
    Predicted Reactivity
    Human: 100%
    Characteristics
    This is a rabbit polyclonal antibody against FCRLA. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human FCRLA
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    Discover our top product FCRLA Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 376 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    FCRLA (Fc Receptor-Like A (FCRLA))
    Alternative Name
    FCRLA (FCRLA Products)
    Background
    Receptors for the Fc fragment of IgG, or FCGRs, are cell surface glycoproteins of the Ig superfamily (IgSF). These receptors mediate phagocytosis of IgG-coated pathogens and promote activation of effector cells, leading to inflammatory responses and antibody-mediated cellular cytotoxicity. FCRLA may be implicated in B-cell differentiation and lymphomagenesis.Receptors for the Fc fragment of IgG, or FCGRs (see MIM 146790), are cell surface glycoproteins of the Ig superfamily (IgSF). These receptors mediate phagocytosis of IgG-coated pathogens and promote activation of effector cells, leading to inflammatory responses and antibody-mediated cellular cytotoxicity. All FCGR genes map to human chromosome 1. Additional genes in this region, including FREB, encode FCGR homologs that are selectively expressed in B cells and may be implicated in B-cell development and lymphomagenesis.[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-742 BM471887.1 3-744 743-1338 BC006521.2 558-1153 1339-1684 BX112608.1 318-663 1685-2357 BX649184.1 2243-2915
    Alias Symbols: FCRL, FCRLM1, FCRLX, FCRLb, FCRLc1, FCRLc2, FCRLd, FCRLe, FREB, MGC4595, RP11-474I16.5, FCRX, FCRL1
    Protein Size: 376
    Molecular Weight
    41 kDa
    Gene ID
    84824
    NCBI Accession
    NM_032738, NP_116127
    UniProt
    Q7L513
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