Bestrophin 3 antibody (C-Term)

Catalog No. ABIN2784051

Product Details anti-Bestrophin 3 Antibody

Target: Bestrophin 3 (BEST3)

Binding Specificity: C-Term

Reactivity: Human, Mouse, Cow, Rat, Rabbit, Dog, Horse, Pig, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Bestrophin 3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VPFIWFGNLA TKARNEGRIR DSVDLQSLMT EMNRYRSWCS LLFGYDWVGI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against BEST3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human BEST3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 455 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Bestrophin 3

Target: Bestrophin 3 (BEST3)

Alternative Name: BEST3 (BEST3 Products)

Synonyms: CG12327 antibody, Dmel\\CG12327 antibody, dbest3 antibody, best-3 antibody, BEST3 antibody, VMD2L3 antibody, Vmd2l3 antibody, mBest4 antibody, bestrophin-3 antibody, bestrophin 3 antibody, Bestrophin 3 antibody, BEST3 antibody, Best3 antibody, best3 antibody

Background: BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD, MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries.
Alias Symbols: MGC13168, MGC40411, VMD2L3
Protein Size: 455

Molecular Weight: 51 kDa

Gene ID: 144453

NCBI Accession: NM_152439, NP_689652

UniProt: B5MDI8