NMES1 antibody (N-Term)

Catalog No. ABIN2784037

Product Details anti-NMES1 Antibody

Target: NMES1 (C15ORF48) (Chromosome 15 Open Reading Frame 48 (C15ORF48))

Binding Specificity: N-Term

Reactivity: Human, Dog, Mouse, Rabbit, Rat, Cow, Zebrafish (Danio rerio), Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NMES1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VAAGGASSFA VYSLWKTDVI LDRKKNPEPW ETVDPTVPQK LITINQQWKP

Predicted Reactivity: Cow: 79%, Dog: 79%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against C15orf48. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 83 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-NMES1 antibody (ABIN2784037)

Clayton, Daley, MacDonald, Fernandez-Vizarra, Bottegoni, ONeil, Major, Griffin, Zhuang, Adewoye, Woolcock, Jones, Goodyear, Elmesmari, Filer, Tennant, Alivernini, Buckley, Pitceathly et al.: "Inflammation causes remodeling of mitochondrial cytochrome c oxidase mediated by the bifunctional gene C15orf48. ..." in: Science advances, Vol. 7, Issue 50, pp. eabl5182, (2021) (PubMed).

Target Details for NMES1

Target: NMES1 (C15ORF48) (Chromosome 15 Open Reading Frame 48 (C15ORF48))

Alternative Name: C15orf48 (C15ORF48 Products)

Synonyms: FOAP-11 antibody, NMES1 antibody, Nmes1 antibody, chromosome 15 open reading frame 48 antibody, expressed sequence AA467197 antibody, hypothetical LOC302884 antibody, C15orf48 antibody, AA467197 antibody, MGC105649 antibody

Background: This gene was identified by its low or completely missing expression in esophageal squamous cell carcinomas. Normal expression of the gene occurs in the esophagus, stomach, small intestine, colon and placenta. Alternatively spliced transcript variants that encode the same protein have been identified.
Alias Symbols: FLJ22645, FOAP-11, MGC32925, NMES1
Protein Interaction Partner: TSSK3, ABL2,
Protein Size: 83

Molecular Weight: 9 kDa

Gene ID: 84419

NCBI Accession: NM_032413, NP_115789