Synaptotagmin 3 antibody (N-Term)

Catalog No. ABIN2784032

Product Details anti-Synaptotagmin 3 Antibody

Target: Synaptotagmin 3 (SYT3) (Synaptotagmin III (SYT3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Synaptotagmin 3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VSWKLCWVPW RDKGGSAVGG GPLRKDLGPG VGLAGLVGGG GHHLAAGLGG

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SYT3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SYT3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 590 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-Synaptotagmin 3 antibody (ABIN2784032)

Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).

Target Details for Synaptotagmin 3

Target: Synaptotagmin 3 (SYT3) (Synaptotagmin III (SYT3))

Alternative Name: SYT3 (SYT3 Products)

Synonyms: SytIII antibody, AI385753 antibody, sytIII antibody, SIII antibody, synaptotagmin 3 antibody, synaptotagmin III antibody, SYT3 antibody, Syt3 antibody

Background: SYT3 may be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.
Alias Symbols: DKFZp761O132, SytIII
Protein Interaction Partner: SYNCRIP, AP2A1, SYT5, SNAP25, SYT3,
Protein Size: 590

Molecular Weight: 63 kDa

Gene ID: 84258

NCBI Accession: NM_032298, NP_115674

UniProt: Q9BQG1

Pathways: Synaptic Vesicle Exocytosis