SGPP1 antibody (Middle Region)

Catalog No. ABIN2783990

Product Details anti-SGPP1 Antibody

Target: SGPP1 (Sphingosine-1-Phosphate Phosphatase 1 (SGPP1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio), Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGPP1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: THKYAPFIII GLHLALGIFS FTLDTWSTSR GDTAEILGSG AGIACGSHVT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against SGPP1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SGPP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 441 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SGPP1

Target: SGPP1 (Sphingosine-1-Phosphate Phosphatase 1 (SGPP1))

Alternative Name: SGPP1 (SGPP1 Products)

Synonyms: SGPP1 antibody, MGC142448 antibody, sgpp1 antibody, SPPase1 antibody, AI463453 antibody, SPP antibody, SPP1 antibody, Spph1 antibody, Spp1 antibody, sphingosine-1-phosphate phosphatase 1 antibody, SGPP1 antibody, sgpp1 antibody, Sgpp1 antibody

Background: Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. SGPP1 catalyzes the degradation of S1P via salvage and recycling of sphingosine into long-chain ceramides (Mandala et al., 2000 [PubMed 10859351], Le Stunff et al., 2007 [PubMed 17895250]).
Alias Symbols: SPPase1
Protein Interaction Partner: UBC, ELAVL1, S1PR5,
Protein Size: 441

Molecular Weight: 49 kDa

Gene ID: 81537

NCBI Accession: NM_030791, NP_110418

UniProt: Q9BX95