Plexin A2 antibody (N-Term)

Catalog No. ABIN2783972

Product Details anti-Plexin A2 Antibody

Target: Plexin A2 (Plxna2)

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Plexin A2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SVASYVYNGY SVVFVGTKSG KLKKIRADGP PHGGVQYEMV SVLKDGSPIL

Predicted Reactivity: Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against PLXNA2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PLXNA2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1894 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-Plexin A2 antibody (ABIN2783972)

Budel, Shim, Feng, Zhao, Hisama, Strittmatter: "No association between schizophrenia and polymorphisms of the PlexinA2 gene in Chinese Han Trios." in: Schizophrenia research, Vol. 99, Issue 1-3, pp. 365-6, (2008) (PubMed).

Target Details for Plexin A2

Target: Plexin A2 (Plxna2)

Alternative Name: PLXNA2 (Plxna2 Products)

Synonyms: oct antibody, plxn2 antibody, OCT antibody, PLXN2 antibody, 2810428A13Rik antibody, AA589422 antibody, AW457381 antibody, Plxn2 antibody, mKIAA0463 antibody, plexin A2 antibody, plexin-A2 antibody, PLXNA2 antibody, plxna2 antibody, LOC100078346 antibody, Plxna2 antibody

Background: PLXNA2 is a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C. This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C.
Alias Symbols: FLJ11751, FLJ30634, KIAA0463, OCT, PLXN2
Protein Interaction Partner: CEMIP, FNBP4, UBAP2L, IFT80, HACE1, DHX37,
Protein Size: 1894

Molecular Weight: 211 kDa

Gene ID: 5362

NCBI Accession: NM_025179, NP_079455

UniProt: O75051