UGT2A3 antibody (Middle Region)

Catalog No. ABIN2783942

Product Details anti-UGT2A3 Antibody

Target: UGT2A3 (UDP Glucuronosyltransferase 2 Family, Polypeptide A3 (UGT2A3))

Binding Specificity: Middle Region

Reactivity: Human, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UGT2A3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GIVVFSLGSL FQNVTEEKAN IIASALAQIP QKVLWRYKGK KPSTLGANTR

Predicted Reactivity: Dog: 79%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against UGT2A3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human UGT2A3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 527 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-UGT2A3 antibody (ABIN2783942)

Suzuki, Fujisawa, Ando, Niino, Ohsawa, Shimokata, Ohta: "Alcohol dehydrogenase 2 variant is associated with cerebral infarction and lacunae." in: Neurology, Vol. 63, Issue 9, pp. 1711-3, (2004) (PubMed).

Target Details for UGT2A3

Target: UGT2A3 (UDP Glucuronosyltransferase 2 Family, Polypeptide A3 (UGT2A3))

Alternative Name: UGT2A3 (UGT2A3 Products)

Background: UGT2A3 belongs to the UDP-glycosyltransferase family. UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.
Alias Symbols: FLJ21934
Protein Size: 527

Molecular Weight: 60 kDa

Gene ID: 79799

NCBI Accession: NM_024743, NP_079019

UniProt: Q6UWM9

Pathways: Steroid Hormone Biosynthesis