TMEM135 antibody (N-Term)

Catalog No. ABIN2783894

Product Details anti-TMEM135 Antibody

Target: TMEM135 (Transmembrane Protein 135 (TMEM135))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM135 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: SLKIYAPLYL IAAILRKRKL DYYLHKLLPE ILQSASFLTA NGALYMAFFC

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against TMEM135. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TMEM135

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 458 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TMEM135 antibody (ABIN2783894)

Lee, Higuchi, Ikeda, Macke, Takimoto, Pattnaik, Liu, Chu, Siepka, Krentz, Rubinstein, Kalejta, Thomson, Mullins, Takahashi, Pinto, Ikeda: "Mouse Tmem135 mutation reveals a mechanism involving mitochondrial dynamics that leads to age-dependent retinal pathologies." in: eLife, Vol. 5, (2016) (PubMed).

Suzuki, Yoshitomo-Nakagawa, Maruyama, Suyama, Sugano: "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library." in: Gene, Vol. 200, Issue 1-2, pp. 149-56, (1997) (PubMed).

Target Details for TMEM135

Target: TMEM135 (Transmembrane Protein 135 (TMEM135))

Alternative Name: TMEM135 (TMEM135 Products)

Synonyms: im:6901522 antibody, zgc:162425 antibody, PMP52 antibody, 2810439K08Rik antibody, AW319712 antibody, RGD1309948 antibody, transmembrane protein 135 antibody, transmembrane protein 135 L homeolog antibody, TMEM135 antibody, tmem135 antibody, CpipJ_CPIJ008774 antibody, tmem135.L antibody, Tmem135 antibody

Background: The exact function of TMEM135 remains unknown.
Alias Symbols: DKFZp686I1974, FLJ22104, PMP52
Protein Interaction Partner: UBC,
Protein Size: 458

Molecular Weight: 52 kDa

Gene ID: 65084

NCBI Accession: NM_022918, NP_075069

UniProt: Q86UB9