PORCN antibody (N-Term)

Catalog No. ABIN2783888

Product Details anti-PORCN Antibody

Target: PORCN (Porcupine Homolog (PORCN))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PORCN antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: ACRLLWRLGL PSYLKHASTV AGGFFSLYHF FQLHMVWVVL LSLLCYLVLF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PORCN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PORCN

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 450 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PORCN

Target: PORCN (Porcupine Homolog (PORCN))

Alternative Name: PORCN (PORCN Products)

Synonyms: 15175 antibody, CG6205 antibody, Dmel\\CG6205 antibody, Porc antibody, dmPorc antibody, l(1)17Ac antibody, poc antibody, porc antibody, DHOF antibody, FODH antibody, MG61 antibody, PORC antibody, PPN antibody, porcupine antibody, 2410004O13Rik antibody, AW045557 antibody, DXHXS7465e antibody, Mporc antibody, Mporc-a antibody, Mporc-b antibody, Mporc-c antibody, Mporc-d antibody, Ppn antibody, mMg61 antibody, RGD1564947 antibody, porcupine antibody, porcupine O-acyltransferase antibody, porcupine homolog (Drosophila) antibody, por antibody, PORCN antibody, Porcn antibody

Background: PORCN belongs to the evolutionarily conserved porcupine (Porc) gene family. Genes of the Porc family encode endoplasmic reticulum proteins with multiple transmembrane domains. Porcupine proteins are involved in the processing of Wnt (wingless and int homologue) proteins. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.This gene belongs to the evolutionarily conserved porcupine (Porc) gene family. Genes of the Porc family encode endoplasmic reticulum proteins with multiple transmembrane domains. Porcupine proteins are involved in the processing of Wnt (wingless and int homologue) proteins. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
Alias Symbols: DHOF, FODH, MG61, MGC29687, PORC, PPN, por
Protein Interaction Partner: WNT5B, WNT3A, WNT6, WNT4, WNT7B, WNT1,
Protein Size: 450

Molecular Weight: 51 kDa

Gene ID: 64840

NCBI Accession: NM_022825, NP_073736