RHBDF1 antibody (N-Term)

Catalog No. ABIN2783869

Product Details anti-RHBDF1 Antibody

Target: RHBDF1 (Rhomboid 5 Homolog 1 (RHBDF1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Horse, Cow, Dog, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RHBDF1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KDWEKAPEQA DLTGGALDRS ELERSHLMLP LERGWRKQKE GAAAPQPKVR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against RHBDF1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RHBDF1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 855 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RHBDF1

Target: RHBDF1 (Rhomboid 5 Homolog 1 (RHBDF1))

Alternative Name: RHBDF1 (RHBDF1 Products)

Synonyms: zgc:91984 antibody, C16orf8 antibody, Dist1 antibody, EGFR-RS antibody, gene-89 antibody, gene-90 antibody, hDist1 antibody, C16ORF8 antibody, Dist antibody, Egfr-rs antibody, mKIAA4242 antibody, rhomboid 5 homolog 1 antibody, rhomboid 5 homolog 1a (Drosophila) antibody, RHBDF1 antibody, rhbdf1 antibody, rhbdf1a antibody, Rhbdf1 antibody

Background: RHBDF1 is a seven-transmembrane protein with a long N-terminal cytoplasmic extension that comprises half of the polypeptide sequence, and is found in the endoplasmic reticulum and Golgi, but not on the cell surface. RHBDF1 has a pivotal role in sustaining growth signals in epithelial cancer cells and thus may serve as a therapeutic target for treating epithelial cancers.
Alias Symbols: C16orf8, Dist1, EGFR-RS, FLJ2235, FLJ22357, gene -89, gene -90, hDist1, gene-89, gene-90
Protein Interaction Partner: UBC, TGFA,
Protein Size: 855

Molecular Weight: 97 kDa

Gene ID: 64285

NCBI Accession: NM_022450, NP_071895

UniProt: Q96CC6

Pathways: EGFR Signaling Pathway, Growth Factor Binding