PERP antibody (Middle Region)

Catalog No. ABIN2783850

Product Details anti-PERP Antibody

Target: PERP (TP53 Apoptosis Effector (PERP))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Dog, Rat, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PERP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: FLRVIGGLLA LAAVFQIISL VIYPVKYTQT FTLHANPAVT YIYNWAYGFG

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against PERP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PERP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 193 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PERP

Target: PERP (TP53 Apoptosis Effector (PERP))

Alternative Name: PERP (PERP Products)

Synonyms: KCP1 antibody, KRTCAP1 antibody, PIGPC1 antibody, RP3-496H19.1 antibody, THW antibody, dJ496H19.1 antibody, 1110017A08Rik antibody, kcp1 antibody, krtcap1 antibody, pigpc1 antibody, thw antibody, fk24g11 antibody, wu:fk24g11 antibody, PERP antibody, PERP, TP53 apoptosis effector antibody, PERP, TP53 apoptosis effector S homeolog antibody, PERP antibody, Perp antibody, perp.S antibody, perp antibody

Background: PERP is a component of intercellular desmosome junctions. PERP plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. PERP also plays a role as an effector in the TP53-dependent apoptotic pathway.
Alias Symbols: KCP1, KRTCAP1, PIGPC1, RP3-496H19.1, THW, dJ496H19.1
Protein Size: 193

Molecular Weight: 21 kDa

Gene ID: 64065

NCBI Accession: NM_022121, NP_071404

UniProt: Q96FX8

Pathways: Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity