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Junctophilin 3 antibody (N-Term)

JPH3 Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish (Danio rerio), Guinea Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2783795
  • Target See all Junctophilin 3 (JPH3) Antibodies
    Junctophilin 3 (JPH3)
    Binding Specificity
    • 15
    • 7
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish (Danio rerio), Guinea Pig
    Host
    • 34
    Rabbit
    Clonality
    • 34
    Polyclonal
    Conjugate
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Junctophilin 3 antibody is un-conjugated
    Application
    • 29
    • 16
    • 13
    • 13
    • 11
    • 9
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    SSGGRFNFDD GGSYCGGWED GKAHGHGVCT GPKGQGEYTG SWSHGFEVLG
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 85%, Rat: 100%, Zebrafish: 93%
    Characteristics
    This is a rabbit polyclonal antibody against JPH3. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human JPH3
    Top Product
    Discover our top product JPH3 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 748 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Junctophilin 3 (JPH3)
    Alternative Name
    JPH3 (JPH3 Products)
    Synonyms
    CAGL237 antibody, HDL2 antibody, JP-3 antibody, JP3 antibody, TNRC22 antibody, Jp3 antibody, fc26e06 antibody, si:ch211-255l14.9 antibody, wu:fc26e06 antibody, junctophilin 3 antibody, JPH3 antibody, Jph3 antibody, jph3 antibody
    Background
    Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. JPH3 is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. CAG/CTG repeat expansions at the Huntington's disease (HD)-like 2 locus have been identified in the gene that encodes JPH3 protein. Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. CAG/CTG repeat expansions at the Huntington's disease (HD)-like 2 locus have been identified in this gene, which is a member of the junctophilin gene family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: CAGL237, FLJ44707, HDL2, JP-3, JP3, TNRC22
    Protein Interaction Partner: PPP1CA, SMAD3, BGN, STK24,
    Protein Size: 748
    Molecular Weight
    81 kDa
    Gene ID
    57338
    NCBI Accession
    NM_020655, NP_065706
    UniProt
    Q8WXH2
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