DOLPP1 antibody (N-Term)

Catalog No. ABIN311193

Product Details anti-DOLPP1 Antibody

Target: DOLPP1 (Dolichyl Pyrophosphate Phosphatase 1 (DOLPP1))

Binding Specificity: N-Term

Reactivity: Mouse, Rat, Human, Zebrafish (Danio rerio), Cow, Guinea Pig, Horse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOLPP1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AADGQCSLPA SWRPVTLTHV EYPAGDLSGH LLAYLSLSPV FVIVGFVTLI

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against DOLPP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DOLPP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 238 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DOLPP1

Target: DOLPP1 (Dolichyl Pyrophosphate Phosphatase 1 (DOLPP1))

Alternative Name: DOLPP1 (DOLPP1 Products)

Background: DOLPP1 is a multi-pass membrane proteinBy similarity. It belongs to the dolichyldiphosphatase family. It is required for efficient N-glycosylation and is necessary for maintaining optimal levels of dolichol-linked oligosaccharides. DOLPP1 hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. It does not act on phosphatidate.
Alias Symbols: LSFR2
Protein Interaction Partner: UBC, ELAVL1,
Protein Size: 238

Molecular Weight: 27 kDa

Gene ID: 57171

NCBI Accession: NM_020438, NP_065171

UniProt: Q86YN1