CRLS1 antibody (Middle Region)

Catalog No. ABIN2783750

Product Details anti-CRLS1 Antibody

Target: CRLS1 (CLS) (Cardiolipin Synthase (CLS))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRLS1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: WTIPNMLSMT RIGLAPVLGY LIIEEDFNIA LGVFALAGLT DLLDGFIARN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against CRLS1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CRLS1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 301 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-CRLS1 antibody (ABIN2783750)

Croston, Shepherd, Thapa, Nichols, Lewis, Dabkowski, Jagannathan, Baseler, Hollander: "Evaluation of the cardiolipin biosynthetic pathway and its interactions in the diabetic heart." in: Life sciences, Vol. 93, Issue 8, pp. 313-22, (2013) (PubMed).

Target Details for CRLS1

Target: CRLS1 (CLS) (Cardiolipin Synthase (CLS))

Alternative Name: CRLS1 (CLS Products)

Background: CRLS1 catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
Alias Symbols: C20orf155, CLS1, GCD10, dJ967N21.6, CLS
Protein Interaction Partner: FBXO15, PINK1, UBC, MCM6, MCM7,
Protein Size: 301

Molecular Weight: 32 kDa

Gene ID: 54675

NCBI Accession: NM_019095, NP_061968

UniProt: Q9UJA2