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NDFIP2 antibody (Middle Region)

NDFIP2 Reactivity: Human, Mouse, Cow, Dog, Horse, Rat, Zebrafish (Danio rerio), Guinea Pig, Pig, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2783749
  • Target See all NDFIP2 Antibodies
    NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))
    Binding Specificity
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 16
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Cow, Dog, Horse, Rat, Zebrafish (Danio rerio), Guinea Pig, Pig, Rabbit
    Host
    • 12
    • 4
    Rabbit
    Clonality
    • 14
    • 2
    Polyclonal
    Conjugate
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NDFIP2 antibody is un-conjugated
    Application
    • 8
    • 4
    • 1
    Western Blotting (WB)
    Sequence
    SFCITNTIAG RYGAICGFGL SLIKWILIVR FSDYFTGYFN GQYWLWWIFL
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against NDFIP2. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human NDFIP2
    Top Product
    Discover our top product NDFIP2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 336 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))
    Alternative Name
    NDFIP2 (NDFIP2 Products)
    Synonyms
    MGC68708 antibody, DKFZp459H0627 antibody, N4WBP5A antibody, 0710001O20Rik antibody, 2810436B12Rik antibody, 9130207N19Rik antibody, N4wbp5a antibody, mKIAA1165 antibody, Nedd4 family interacting protein 2 S homeolog antibody, Nedd4 family interacting protein 2 antibody, ndfip2.S antibody, NDFIP2 antibody, ndfip2 antibody, Ndfip2 antibody
    Background
    NDFIP2 activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, and consequently modulates the stability of their targets. As a result, NDFIP2 may control many cellular processes. NDFIP2 recruits ITCH, NEDD4 and SMURF2 to endosomal membranes. NDFIP2 may modulate EGFR signaling.
    Alias Symbols: FLJ25842, KIAA1165, N4wbp5a, N4WBP5A
    Protein Interaction Partner: UBC, NEDD4L, NEDD4, ELAVL1, ITCH, WWP2, SRC, PTEN, LYN, FYN, EGFR, SMURF1, SLC11A2,
    Protein Size: 336
    Molecular Weight
    36 kDa
    Gene ID
    54602
    NCBI Accession
    NM_019080, NP_061953
    UniProt
    Q9NV92
    Pathways
    Negative Regulation of Transporter Activity, SARS-CoV-2 Protein Interactome
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