PCDHGB1 antibody (N-Term)
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- Target See all PCDHGB1 Antibodies
- PCDHGB1 (Protocadherin gamma Subfamily B, 1 (PCDHGB1))
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Binding Specificity
- N-Term
- Reactivity
- Human, Rabbit, Mouse, Rat, Cow, Zebrafish (Danio rerio), Dog, Guinea Pig, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PCDHGB1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- SPDGSKYPVL LLEKPLDREH QSSHRLILTA MDGGDPPLSG TTHIWIRVTD
- Predicted Reactivity
- Cow: 85%, Dog: 92%, Guinea Pig: 90%, Horse: 83%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%, Zebrafish: 83%
- Characteristics
- This is a rabbit polyclonal antibody against PCDHGB1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human PCDHGB1
- Top Product
- Discover our top product PCDHGB1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 810 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PCDHGB1 (Protocadherin gamma Subfamily B, 1 (PCDHGB1))
- Alternative Name
- PCDHGB1 (PCDHGB1 Products)
- Synonyms
- PCDH-GAMMA-B1 antibody, protocadherin gamma subfamily B, 1 antibody, PCDHGB1 antibody, Pcdhgb1 antibody
- Background
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PCDHGB1 is a single-pass type I membrane protein. It contains 6 cadherin domains. PCDHGB1 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
Alias Symbols: MGC119466, MGC119467, MGC119469, PCDH-GAMMA-B1
Protein Size: 810 - Molecular Weight
- 85 kDa
- Gene ID
- 56104
- NCBI Accession
- NM_032095, NP_115266
- UniProt
- Q3SY75
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