PCDHA11 antibody (N-Term)

Catalog No. ABIN2783720

Product Details anti-PCDHA11 Antibody

Target: PCDHA11 (Protocadherin alpha 11 (PCDHA11))

Binding Specificity: N-Term

Reactivity: Human, Cow, Guinea Pig, Horse, Mouse, Pig, Rabbit, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHA11 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RLSKNEYFSL DSPTNGKQIK RLSLILKKSL DREKTPELNL LLTATDGGKP

Predicted Reactivity: Cow: 93%, Guinea Pig: 77%, Horse: 92%, Human: 100%, Mouse: 93%, Pig: 85%, Rabbit: 86%, Rat: 91%

Characteristics: This is a rabbit polyclonal antibody against PCDHA11. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 810 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PCDHA11

Target: PCDHA11 (Protocadherin alpha 11 (PCDHA11))

Alternative Name: PCDHA11 (PCDHA11 Products)

Synonyms: CNR7 antibody, CNRN7 antibody, CNRS7 antibody, CRNR7 antibody, PCDH-ALPHA11 antibody, A830022B16Rik antibody, Cnr7 antibody, Crnr7 antibody, protocadherin alpha 11 antibody, PCDHA11 antibody, Pcdha11 antibody

Background: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
Alias Symbols: CNR7, CNRN7, CNRS7, CRNR7, PCDH-ALPHA11
Protein Interaction Partner: UBC,
Protein Size: 810

Molecular Weight: 85 kDa

Gene ID: 56138

NCBI Accession: NM_031861, NP_114067