PRIM2 antibody (Middle Region)

Catalog No. ABIN2783685

Product Details anti-PRIM2 Antibody

Target: PRIM2 (Primase, DNA, Polypeptide 2 (58kDa) (PRIM2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRIM2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QDFLKDSQLQ FEAISDEEKT LREQEIVASS PSLSGLKLGF KSIYKPPFAS

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against PRIM2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PRIM2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 340 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PRIM2

Target: PRIM2 (Primase, DNA, Polypeptide 2 (58kDa) (PRIM2))

Alternative Name: PRIM2 (PRIM2 Products)

Synonyms: prim2a antibody, AI323589 antibody, Pola3 antibody, PRIM2A antibody, p58 antibody, DNA primase subunit 2 antibody, DNA primase, p58 subunit antibody, prim2 antibody, Prim2 antibody, PRIM2 antibody

Background: The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.
Alias Symbols: RP3-401D24.1, MGC75142, PRIM2A, p58
Protein Interaction Partner: FAM96B, CIAO1, UBC, NEDD8, POLA2, KDM1A, SUV39H1, POLA1, MMS19, PRIM1, ELAVL1, SUMO2, RAE1,
Protein Size: 340

Molecular Weight: 37 kDa

Gene ID: 5558

UniProt: Q5JU42

Pathways: Telomere Maintenance, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, SARS-CoV-2 Protein Interactome