TTC5 antibody (C-Term)

Catalog No. ABIN2783601

Product Details anti-TTC5 Antibody

Target: TTC5 (Tetratricopeptide Repeat Domain 5 (TTC5))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTC5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GDSVAIPEPN LRLHRIQHKG KDYSFSSVRV ETPLLLVVNG KPQGSSSQAV

Predicted Reactivity: Cow: 100%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against TTC5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TTC5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 440 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TTC5

Target: TTC5 (Tetratricopeptide Repeat Domain 5 (TTC5))

Alternative Name: TTC5 (TTC5 Products)

Synonyms: TTC5 antibody, ttc5 antibody, wu:fi33h05 antibody, wu:fy81e07 antibody, zgc:112059 antibody, Strap antibody, 5930437N14 antibody, AW743060 antibody, tetratricopeptide repeat domain 5 L homeolog antibody, tetratricopeptide repeat domain 5 antibody, ttc5.L antibody, TTC5 antibody, ttc5 antibody, Ttc5 antibody

Background: TTC5 is an adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. It is required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. It prevents p53/TP53 degradation by MDM2.
Alias Symbols: Strap
Protein Interaction Partner: AR, NR3C1, ESR1, CAMK2D, CAMK2B, UBC, CAND1, COPS5, CUL3, ELAVL1,
Protein Size: 440

Molecular Weight: 49 kDa

Gene ID: 91875

NCBI Accession: NM_138376, NP_612385

UniProt: Q8N0Z6

Pathways: Chromatin Binding