AGXT2 antibody (N-Term)

Catalog No. ABIN2783579

Product Details anti-AGXT2 Antibody

Target: AGXT2 (Alanine Glyoxylate Aminotransferase 2 (AGXT2))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Rabbit, Cow, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGXT2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TSVTKLSLHT KPRMPPCDFM PERYQSLGYN RVLEIHKEHL SPVVTAYFQK

Predicted Reactivity: Cow: 86%, Dog: 79%, Horse: 79%, Human: 100%, Mouse: 77%, Rabbit: 79%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against AGXT2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AGXT2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 514 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-AGXT2 antibody (ABIN2783579)

Baker, Cramer, Kennedy, Assimos, Holmes: "Glycolate and glyoxylate metabolism in HepG2 cells." in: American journal of physiology. Cell physiology, Vol. 287, Issue 5, pp. C1359-65, (2004) (PubMed).

Target Details for AGXT2

Target: AGXT2 (Alanine Glyoxylate Aminotransferase 2 (AGXT2))

Alternative Name: AGXT2 (AGXT2 Products)

Synonyms: AGT2 antibody, DAIBAT antibody, AI303810 antibody, AI663818 antibody, T19P19.50 antibody, T19P19_50 antibody, alanine:glyoxylate aminotransferase 2 antibody, im:7153274 antibody, zgc:114195 antibody, alanine--glyoxylate aminotransferase 2 antibody, alanine-glyoxylate aminotransferase 2 antibody, alanine:glyoxylate aminotransferase 2 antibody, AGXT2 antibody, Agxt2 antibody, AGT2 antibody, agxt2 antibody

Background: The protein encoded by this gene is a class III pyridoxal-phosphate-dependent mitochondrial aminotransferase. It catalyzes the conversion of glyoxylate to glycine using L-alanine as the amino donor.
Alias Symbols: AGT2, DAIBAT
Protein Interaction Partner: CYP2E1, ALDOB,
Protein Size: 514

Molecular Weight: 52 kDa

Gene ID: 64902

NCBI Accession: NM_031900, NP_114106

UniProt: Q9BYV1

Pathways: Monocarboxylic Acid Catabolic Process