CHST6 antibody (Middle Region)

Catalog No. ABIN406023

Product Details anti-CHST6 Antibody

Target: CHST6 (Carbohydrate (N-Acetylglucosamine 6-O) Sulfotransferase 6 (CHST6))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Dog, Cow, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHST6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QELCAGALQL LGYRPVYSED EQRNLALDLV LPRGLNGFTW ASSTASHPRN

Predicted Reactivity: Cow: 79%, Dog: 83%, Guinea Pig: 82%, Horse: 86%, Human: 100%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against CHST6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CHST6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 395 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHST6

Target: CHST6 (Carbohydrate (N-Acetylglucosamine 6-O) Sulfotransferase 6 (CHST6))

Alternative Name: CHST6 (CHST6 Products)

Background: CHST6 catalyzes the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues of keratan. It mediates sulfation of keratan in cornea. Keratan sulfate plays a central role in maintaining corneal transparency. CHST6 acts on the non-reducing terminal GlcNAc of short and long carbohydrate substrates that have poly-N-acetyllactosamine structures.
Alias Symbols: MCDC1
Protein Size: 395

Molecular Weight: 44 kDa

Gene ID: 4166

NCBI Accession: NM_021615, NP_067628

UniProt: Q9GZX3

Pathways: Glycosaminoglycan Metabolic Process