TRMT5 antibody (Middle Region)

Catalog No. ABIN2783538

Product Details anti-TRMT5 Antibody

Target: TRMT5 (tRNA Methyltransferase 5 (TRMT5))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Rabbit, Horse, Cow, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRMT5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EMLCITFQIP ASVLYKNQTR NPENHEDPPL KRQRTAEAFS DEKTQIVSNT

Predicted Reactivity: Cow: 77%, Dog: 85%, Horse: 83%, Human: 100%, Pig: 77%, Rabbit: 75%, Rat: 82%

Characteristics: This is a rabbit polyclonal antibody against TRMT5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TRMT5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 509 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRMT5

Target: TRMT5 (tRNA Methyltransferase 5 (TRMT5))

Alternative Name: TRMT5 (TRMT5 Products)

Synonyms: RGD1306567 antibody, 2610027O18Rik antibody, mKIAA1393 antibody, wu:fi28b08 antibody, KIAA1393 antibody, TRM5 antibody, tRNA methyltransferase 5 antibody, TRM5 tRNA methyltransferase 5 antibody, TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae) antibody, Trmt5 antibody, TRMT5 antibody, trmt5 antibody

Background: TRNAs contain as many as 13 or 14 nucleotides that are modified posttranscriptionally by enzymes that are highly specific for particular nucleotides in the tRNA structure. TRMT5 methylates the N1 position of guanosine-37 (G37) in selected tRNAs using S-adenosyl methionine.tRNAs contain as many as 13 or 14 nucleotides that are modified posttranscriptionally by enzymes that are highly specific for particular nucleotides in the tRNA structure. TRMT5 methylates the N1 position of guanosine-37 (G37) in selected tRNAs using S-adenosyl methionine (Brule et al., 2004 [PubMed 15248782]).[supplied by OMIM].
Alias Symbols: KIAA1393, MGC111453, TRM5
Protein Interaction Partner: UBC,
Protein Size: 509

Molecular Weight: 58 kDa

Gene ID: 57570

NCBI Accession: NM_020810, NP_065861

UniProt: Q32P41