UGCGL2 antibody (Middle Region)

Catalog No. ABIN2783532

Product Details anti-UGCGL2 Antibody

Target: UGCGL2 (UGT2) (UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGT2))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Cow, Rabbit, Dog, Horse, Mouse, Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UGCGL2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LCNNPKTKES KLKAAARIVP EWVEYDAEIR QLLDHLENKK QDTILTHDEL

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 91%, Human: 100%, Mouse: 91%, Pig: 91%, Rabbit: 82%, Rat: 100%, Yeast: 90%

Characteristics: This is a rabbit polyclonal antibody against UGCGL2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human UGCGL2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1516 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for UGCGL2

Target: UGCGL2 (UGT2) (UDP-Glucose Glycoprotein Glucosyltransferase 2 (UGT2))

Alternative Name: UGCGL2 (UGT2 Products)

Synonyms: UGCGL2 antibody, ugcgl2 antibody, im:7146988 antibody, wu:fi13a08 antibody, HUGT2 antibody, UGT2 antibody, 1810064L21Rik antibody, 3110001A05Rik antibody, 3110027P15Rik antibody, A230065J02Rik antibody, AW047562 antibody, Ugcgl2 antibody, UDP-glucose glycoprotein glucosyltransferase 2 antibody, UGGT2 antibody, uggt2 antibody, Uggt2 antibody

Background: UGCGL2 recognizes glycoproteins with minor folding defects. UGCGL2 reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.
Alias Symbols: FLJ10873, FLJ11485, HUGT2, MGC117360, MGC150689, MGC87276, UGT2, UGCGL2
Protein Interaction Partner: APPBP2, FBXO6, METTL23, OS9, APP, BABAM1, BRE, SEP15,
Protein Size: 1516

Molecular Weight: 172 kDa

Gene ID: 55757

NCBI Accession: NM_020121, NP_064506

UniProt: Q9NYU1

Pathways: SARS-CoV-2 Protein Interactome