CMAS antibody (N-Term)

Catalog No. ABIN2783528

Product Details anti-CMAS Antibody

Target: CMAS (Cytidine Monophosphate N-Acetylneuraminic Acid Synthetase (CMAS))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Zebrafish (Danio rerio), Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CMAS antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GRGVEKPPHL AALILARGGS KGIPLKNIKH LAGVPLIGWV LRAALDSGAF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CMAS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CMAS

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 434 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CMAS

Target: CMAS (Cytidine Monophosphate N-Acetylneuraminic Acid Synthetase (CMAS))

Alternative Name: CMAS (CMAS Products)

Synonyms: CSS antibody, cmas antibody, cmas1 antibody, si:dkey-183c2.1 antibody, wu:fj16c12 antibody, zgc:136241 antibody, AW208911 antibody, CMPNeu5Ac antibody, D6Bwg0250e antibody, cytidine monophosphate N-acetylneuraminic acid synthetase antibody, cytidine monophosphate N-acetylneuraminic acid synthetase a antibody, cytidine monophospho-N-acetylneuraminic acid synthetase antibody, CMAS antibody, Cmas antibody, cmasa antibody, cmas antibody

Background: CMAS is an enzyme that catalyzes the activation of Neu5Ac to Cytidine 5-prime-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), which provides the substrate required for the addition of sialic acid. Sialic acids of cell surface glycoproteins and glycolipids play a pivotal role in the structure and function of animal tissues. The pattern of cell surface sialylation is highly regulated during embryonic development, and changes with stages of differentiation. Studies of a similar murine protein suggest that this protein localizes to the nucleus.The enzyme encoded by this gene catalyzes the activation of Neu5Ac to Cytidine 5-prime-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), which provides the substrate required for the addition of sialic acid. Sialic acids of cell surface glycoproteins and glycolipids play a pivotal role in the structure and function of animal tissues. The pattern of cell surface sialylation is highly regulated during embryonic development, and changes with stages of differentiation. Studies of a similar murine protein suggest that this protein localizes to the nucleus.
Alias Symbols: CSS
Protein Interaction Partner: SUMO2, SUMO3, UBC, FBXO6, APP, SIGLEC12,
Protein Size: 434

Molecular Weight: 48 kDa

Gene ID: 55907

NCBI Accession: NM_018686, NP_061156

UniProt: Q8NFW8