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BHMT2 antibody (Middle Region)

BHMT2 Reactivity: Human, Mouse, Rat, Cow, Horse, Dog, Guinea Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2783509
  • Target See all BHMT2 Antibodies
    BHMT2 (Betaine--Homocysteine S-Methyltransferase 2 (BHMT2))
    Binding Specificity
    • 6
    • 4
    • 2
    • 1
    • 1
    Middle Region
    Reactivity
    Human, Mouse, Rat, Cow, Horse, Dog, Guinea Pig
    Host
    • 17
    • 4
    Rabbit
    Clonality
    • 20
    • 1
    Polyclonal
    Conjugate
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BHMT2 antibody is un-conjugated
    Application
    • 11
    • 8
    • 5
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    GFVDLPEYPF GLESRVATRW DIQKYAREAY NLGVRYIGGC CGFEPYHIRA
    Predicted Reactivity
    Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 93%, Rat: 93%
    Characteristics
    This is a rabbit polyclonal antibody against BHMT2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human BHMT2
    Top Product
    Discover our top product BHMT2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 363 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    BHMT2 (Betaine--Homocysteine S-Methyltransferase 2 (BHMT2))
    Alternative Name
    BHMT2 (BHMT2 Products)
    Synonyms
    C81077 antibody, D13Ucla2 antibody, BHMT2 antibody, DKFZp469M1332 antibody, bhmt-2 antibody, betaine--homocysteine S-methyltransferase 2 antibody, betaine-homocysteine methyltransferase 2 antibody, betaine-homocysteine S-methyltransferase 2 antibody, S-methylmethionine--homocysteine S-methyltransferase BHMT2 antibody, BHMT2 antibody, Bhmt2 antibody, LOC100073266 antibody
    Background
    Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: FLJ20001
    Protein Interaction Partner: APP,
    Protein Size: 363
    Molecular Weight
    40 kDa
    Gene ID
    23743
    NCBI Accession
    NM_017614, NP_060084
    UniProt
    Q9H2M3
    Pathways
    Methionine Biosynthetic Process
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