LIAS antibody (N-Term)

Catalog No. ABIN2783475

Product Details anti-LIAS Antibody

Target: LIAS (Lipoic Acid Synthetase (LIAS))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Zebrafish (Danio rerio), Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIAS antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LLQNGPDLQD FVSGDLADRS TWDEYKGNLK RQKGERLRLP PWLKTEIPMG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against LIAS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LIAS

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 372 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LIAS

Target: LIAS (Lipoic Acid Synthetase (LIAS))

Alternative Name: LIAS (LIAS Products)

Synonyms: LAS antibody, LIP1 antibody, LS antibody, PDHLD antibody, 2900022L22Rik antibody, 4933425M12Rik antibody, 7a5ex antibody, C77512 antibody, mLip1 antibody, zgc:66080 antibody, Lip-syn antibody, lipoyl synthase, mitochondrial antibody, lipoic acid synthetase antibody, lipoyl synthase antibody, lipoic acid synthetase S homeolog antibody, Lipoyl synthase, mitochondrial antibody, LOC5571879 antibody, THAPSDRAFT_31845 antibody, THAPSDRAFT_31673 antibody, UREG_00501 antibody, LOAG_04019 antibody, TERG_02451 antibody, Tsp_01534 antibody, LIAS antibody, Lias antibody, lias antibody, lias.S antibody, umc2251 antibody

Background: LIAS belongs to the biotin and lipoic acid synthetases family. It localizes in mitochondrion and plays an important role in alpha-(+)-lipoic acid synthesis. It may also function in the sulfur insertion chemistry in lipoate biosynthesis.The protein encoded by this gene belongs to the biotin and lipoic acid synthetases family. It localizes in mitochondrion and plays an important role in alpha-(+)-lipoic acid synthesis. It may also function in the sulfur insertion chemistry in lipoate biosynthesis. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.The protein encoded by this gene belongs to the biotin and lipoic acid synthetases family. It localizes in mitochondrion and plays an important role in alpha-(+)-lipoic acid synthesis. It may also function in the sulfur insertion chemistry in lipoate biosynthesis. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.
Alias Symbols: HUSSY-01, LAS, LIP1, MGC23245, LS, PDHLD
Protein Size: 372

Molecular Weight: 39 kDa

Gene ID: 11019

NCBI Accession: NM_006859, NP_006850

UniProt: O43766

Pathways: Tube Formation