METTL1 antibody (Middle Region)

Catalog No. ABIN2783457

Product Details anti-METTL1 Antibody

Target: METTL1 (Methyltransferase Like 1 (METTL1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae, Goat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This METTL1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KGQLTKMFFL FPDPHFKRTK HKWRIISPTL LAEYAYVLRV GGLVYTITDV

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 87%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against METTL1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human METTL1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 301 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for METTL1

Target: METTL1 (Methyltransferase Like 1 (METTL1))

Alternative Name: METTL1 (METTL1 Products)

Synonyms: Dmel\\CG4045 antibody, EG:22E5.4 antibody, C12orf1 antibody, TRM8 antibody, TRMT8 antibody, YDL201w antibody, 2810012D02Rik antibody, CG4045 gene product from transcript CG4045-RA antibody, methyltransferase like 1 antibody, methyltransferase like 1 L homeolog antibody, tRNA (guanine46-N7)-methyltransferase antibody, tRNA (guanine-N(1)-)-methyltransferase antibody, tRNA (guanine-N7-)-methyltransferase antibody, CG4045 antibody, METTL1 antibody, Mettl1 antibody, mettl1.L antibody, CAALFM_C404810CA antibody, LOC100280508 antibody, LOC732983 antibody

Background: METTL1 contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation.This gene is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation. Alternative splice variants encoding different protein isoforms have been described for this gene. A pseudogene has been identified on chromosome X.
Alias Symbols: C12orf1, TRM8, YDL201w
Protein Interaction Partner: WDR4, AKT1, TRM8, PDLIM5, ARPC2, ACTR2, ACTR3, ARPC1B, ARPC4, ARPC5, TOM1L1, KIAA0101, UBE3A, TPD52L2, PRDX2, PRKDC, PRDX1, NUCB1, GTF2I, DR1, AARS, TP53RK, NIF3L1, CTPS2, NPLOC4, DNAAF5, IPO11, TPRKB, CACYBP, KIAA1279, METTL18, UBC, RPS6KA1, RPS6KA3,
Protein Size: 301

Molecular Weight: 34 kDa

Gene ID: 4234

NCBI Accession: NM_005371, NP_005362

UniProt: Q9UBP6