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PAPSS2 antibody (C-Term)

PAPSS2 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio) WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2783448
  • Target See all PAPSS2 Antibodies
    PAPSS2 (3'-phosphoadenosine 5'-phosphosulfate Synthase 2 (PAPSS2))
    Binding Specificity
    • 9
    • 8
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    C-Term
    Reactivity
    • 44
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)
    Host
    • 38
    • 6
    Rabbit
    Clonality
    • 40
    • 4
    Polyclonal
    Conjugate
    • 19
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PAPSS2 antibody is un-conjugated
    Application
    • 27
    • 25
    • 23
    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    PARHNEFDFI SGTRMRKLAR EGENPPDGFM APKAWKVLTD YYRSLEKN
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    Characteristics
    This is a rabbit polyclonal antibody against PAPSS2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human PAPSS2
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    Discover our top product PAPSS2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 619 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • Target
    PAPSS2 (3'-phosphoadenosine 5'-phosphosulfate Synthase 2 (PAPSS2))
    Alternative Name
    PAPSS2 (PAPSS2 Products)
    Synonyms
    ATPSK2 antibody, BCYM4 antibody, SK2 antibody, 1810018P12Rik antibody, AI159688 antibody, AtpsU2 antibody, Atpsk2 antibody, Sk2 antibody, bm antibody, Papss1 antibody, id:ibd2761 antibody, papss2 antibody, sb:cb868 antibody, wu:fb12e05 antibody, zgc:55851 antibody, zgc:85655 antibody, PAPSS2 antibody, zgc:153748 antibody, 3'-phosphoadenosine 5'-phosphosulfate synthase 2 antibody, 3'-phosphoadenosine 5'-phosphosulfate synthase 2b antibody, 3'-phosphoadenosine 5'-phosphosulfate synthase 2a antibody, PAPSS2 antibody, Papss2 antibody, papss2b antibody, papss2.S antibody, LOAG_05620 antibody, papss2 antibody, papss2a antibody
    Background
    Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. PAPSS2 is one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene.Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. This gene encodes one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene.
    Alias Symbols: ATPSK2, SK2
    Protein Interaction Partner: RIC8A, ARIH2, GTF3C4, TXNRD1, TUBB2A, HNRNPA2B1, APEX1, UBD, UBC, APP, Papss1, VHL,
    Protein Size: 619
    Molecular Weight
    70 kDa
    Gene ID
    9060
    NCBI Accession
    NM_001015880, NP_001015880
    Pathways
    Glycosaminoglycan Metabolic Process, Ribonucleoside Biosynthetic Process
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