MAP4K2 antibody (N-Term)
-
- Target See all MAP4K2 Antibodies
- MAP4K2 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2))
-
Binding Specificity
- N-Term
-
Reactivity
- Human, Mouse, Rat, Cow, Guinea Pig, Zebrafish (Danio rerio), Dog, Horse, Pig, Rabbit
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This MAP4K2 antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- HLHPMRALML MSKSSFQPPK LRDKTRWTQN FHHFLKLALT KNPKKRPTAE
- Predicted Reactivity
- Cow: 100%, Dog: 93%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 85%, Rat: 100%, Zebrafish: 92%
- Characteristics
- This is a rabbit polyclonal antibody against MAP4K2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human MAP4K2
- Top Product
- Discover our top product MAP4K2 Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 820 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- MAP4K2 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2))
- Alternative Name
- MAP4K2 (MAP4K2 Products)
- Synonyms
- BL44 antibody, GCK antibody, RAB8IP antibody, AI385662 antibody, Rab8ip antibody, MAP4K2 antibody, dZ150L22.2 antibody, map4k2l antibody, map4k2l-2 antibody, map4k3l antibody, si:dz150l22.2 antibody, si:dz263j20.1 antibody, zgc:136670 antibody, mitogen-activated protein kinase kinase kinase kinase 2 antibody, mitogen activated protein kinase kinase kinase kinase 2 antibody, MAP4K2 antibody, Map4k2 antibody, LOC103346779 antibody, map4k2 antibody
- Background
-
MAP4K2 is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.
Alias Symbols: BL44, GCK, RAB8IP
Protein Interaction Partner: HSP90AA1, UBC, MAP3K11, MAP3K1, POT1, MCM3AP-AS1, NACAD, SNRNP35, PRDX4, SERPINA4, HNRNPA2B1, XRCC6, DEFB1, TRAF2, RAB8A, MAP2K4,
Protein Size: 820 - Molecular Weight
- 91 kDa
- Gene ID
- 5871
- NCBI Accession
- NM_004579, NP_004570
- UniProt
- Q12851
-