Laminin beta 1 antibody (Middle Region)

Catalog No. ABIN2783423

Product Details anti-Laminin beta 1 Antibody

Target: Laminin beta 1 (LAMB1) (Laminin, beta 1 (LAMB1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Horse, Cow, Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Laminin beta 1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VEELKRKAAQ NSGEAEYIEK VVYTVKQSAE DVKKTLDGEL DEKYKKVENL

Predicted Reactivity: Cow: 93%, Dog: 79%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 85%, Rat: 100%, Yeast: 75%

Characteristics: This is a rabbit polyclonal antibody against LAMB1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LAMB1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1786 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-Laminin beta 1 antibody (ABIN2783423)

Puttabyatappa, Irwin, Martin, Mesquitta, Veiga-Lopez, Padmanabhan: "Developmental Programming: Gestational Exposure to Excess Testosterone Alters Expression of Ovarian Matrix Metalloproteases and Their Target Proteins" in: Reproductive sciences (Thousand Oaks, Calif.), pp. 1933719117697130, (2017) (PubMed).

Target Details for Laminin beta 1

Target: Laminin beta 1 (LAMB1) (Laminin, beta 1 (LAMB1))

Alternative Name: LAMB1 (LAMB1 Products)

Synonyms: CLM antibody, LIS5 antibody, fc20b05 antibody, gup antibody, lamb1 antibody, sb:cb95 antibody, wu:fc20b05 antibody, Lamb1-1 antibody, LAMB1 antibody, C77966 antibody, C80098 antibody, C81607 antibody, D130003D08Rik antibody, Lamb-1 antibody, laminin subunit beta 1 antibody, laminin, beta 1a antibody, laminin B1 antibody, LAMB1 antibody, lamb1a antibody, Lamb1 antibody, lamb1 antibody

Background: Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, n
Alias Symbols: CLM, MGC142015
Protein Interaction Partner: PA2G4, ANTXR2, KIAA1033, POLR2E, HECW2, ERBB2IP, UBC, PDIA3, DPY30, HSPD1, NQO1, FBXO6, ATXN7L2, GFI1B, Lama1, LAMC1, Ogg1, EIF3I, ATXN7, CACNA1A, TGFB1, COL6A1, ACHE,
Protein Size: 1786

Molecular Weight: 198 kDa

Gene ID: 3912

NCBI Accession: NM_002291, NP_002282

UniProt: P07942