GSTA3 antibody (Middle Region)
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- Target See all GSTA3 Antibodies
- GSTA3 (Glutathione S-Transferase alpha 3 (GSTA3))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Sheep
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GSTA3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- SSLISNFPLL KALKTRISNL PTVKKFLQPG SPRKPPADAK ALEEARKIFR
- Predicted Reactivity
- Human: 100%, Mouse: 79%, Sheep: 77%
- Characteristics
- This is a rabbit polyclonal antibody against GSTA3. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human GSTA3
- Top Product
- Discover our top product GSTA3 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 222 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- GSTA3 (Glutathione S-Transferase alpha 3 (GSTA3))
- Alternative Name
- GSTA3 (GSTA3 Products)
- Synonyms
- GSTA3 antibody, GST antibody, GSTA1 antibody, GSTA3-3 antibody, GTA3 antibody, GSTA2 antibody, Gst2-3 antibody, Yc2 antibody, glutathione S-transferase alpha 3 antibody, glutathione S-transferase A2 antibody, glutathione S-transferase antibody, glutathione S-transferase, alpha 3 antibody, glutathione S-transferase Yc antibody, GSTA3 antibody, LOC474938 antibody, gsta3 antibody, Gsta3 antibody, LOC100328911 antibody
- Background
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Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined.
Alias Symbols: GSTA3-3, GTA3, MGC22232
Protein Interaction Partner: BAG3, APP,
Protein Size: 222 - Molecular Weight
- 25 kDa
- Gene ID
- 2940
- NCBI Accession
- NM_000847, NP_000838
- UniProt
- Q16772
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